A nationwide survey to assess COVID-19's impact on health and lifestyle in Saudi Arabia.

OBJECTIVE: Since COVID-19 outbreak, there is a lack of extensive literature on the impact of the COVID-19 pandemic on health and lifestyle. The aim of the study was (1) to assess the COVID-19 related knowledge and its socio-demographic correlates in individuals from different parts of Saudi Arabia, (2) to evaluate the health-related impact and lifestyle changes in the Saudi population because of the COVID-19 pandemic, and (3) to determine the perceived importance of future preparedness among residents. MATERIALS AND METHODS: A cross-sectional study was conducted in different regions of Saudi Arabia from  December 2020 to February 2022. Individuals aged 18 years and above were surveyed from different parts of the county. The questionnaires were made available online, and the participants filled them in. The questionnaires included COVID-19 related knowledge, the assessment of the health impact of COVID-19, perceived importance of future preparation for the pandemic, lifestyles, and demographics. Likert plot, univariate and multivariate logistic regression analyses were done. RESULTS: A total of 616 respondents were included in the study. The majority of the repondents were female (58.6%).  36% of the respondents considered their knowledge level on the novel coronavirus as very good. 43.5% said their knowledge level on preventing the spread of the novel coronavirus is excellent. Retired people were 84% (aOR 0.16, 95% CI 0.03-0.78) less likely of higher physical activity as compared to working (≥40 hrs/week) professionals. Separated/divorced/widowed and singles were 3.65 times (aOR 3.65, 95% CI 1.34-9.94) and 2.23 times (aOR 2.23, 95% CI 1.28-3.89) more likely of higher screen time as compared to those who were married/cohabitation/common-law. CONCLUSIONS: Lifestyle in Saudi Arabia has changed significantly due to the COVID-19 pandemic. Healthy habits such as eating at home and cooking at home have increased, while unhealthy habits such as reduced physical activity, screen time have increased.

Association of indoor air pollution on cognitive dysfunction among elderly.

OBJECTIVE: Cognitive dysfunction among the elderly is a devastating condition preceded by accumulation of neuropathology leading to accelerated cognitive decline. Many epidemiologic studies have reported the relation between indoor air pollution exposure and cognitive impairment. To clarify the nature of the association, a comprehensive systematic review and meta-analysis were performed. MATERIALS AND METHODS: The analysis included all observational studies, including cross-sectional studies, prospective and retrospective cohort studies. Experimental studies, randomized controlled trials (RCTs), and controlled clinical trials were excluded. Studies on the relationships of indoor air pollution and cognition published before 30 April 2021 which are peer-reviewed scientific publications available in English were included after performing a structured literature search through electronic databases, including PubMed, Embase, Cochrane Library, and clinical trial.gov. A total of 146 articles were collected, and after screening thoroughly only, 9 studies were selected. Meta-analysis for the final set of selected studies was performed using the R software. RESULTS: The quality of all the studies was adequate as almost all reported an association between at least one pollutant and cognitive dysfunction. However, relatively few studies considered outcomes that provide the most substantial evidence for a causal effect. In total, 5 studies have reported on cognitive function. The pooled mean of cognitive function was 12.16 (95% CI: 10.73 to 13.58). However, the heterogeneity was very high (I2=100%; chi-square test for heterogeneity = p<0.001). We used a modified JBI structured risk of the bias assessment tool, and it was minimal among the included studies as most of the studies have followed a random sampling method and explicitly mention it in their methods. CONCLUSIONS: Exposure to indoor air pollution through fuels used for cooking and heating was significantly associated with cognitive dysfunction among elderly women. Given the limitations, a more extensive meta-analysis and longitudinal studies are recommended to investigate the biological mechanism behind the impact of indoor air pollution on cognitive health.